Analisis kadar glukosa, hemoglobin, dan kolesterol mencit (Mus musculus) setelah diinduksi aspartam

Tyastirin, Esti and Purnamasari, Risa and Hidayati, Irul and Agustina, Eva and Hadi, Moch. Irfan and Lusiana, Nova and Kumalasari, Mei Lina Fitri (2018) Analisis kadar glukosa, hemoglobin, dan kolesterol mencit (Mus musculus) setelah diinduksi aspartam. Biotropic: The Journal of Tropical Biology, 2 (2). pp. 119-125. ISSN 2580 - 5029

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Abstract

Aspartame has a lower calorie rating than other sweeteners. for example, cyclamate, lactose, saccharin, fructose and maltosa. Although it has low calorie, aspartame have 60 times sweeter than sugar (sucrose). Induction of aspartame can cause elevated levels of blood glucose and damage to the pancreatic β cells of mice. The purpose of this study was to analyze the dosing of aspartame levels; 13 mg/Kg body weight, 39 mg/Kg and 78 mg/Kg and those effect to the levels of glucose, cholesterol and haemoglobin of female mice (Mus musculus). The methode of research laboratory experiments using a complete randomized design (RAL). This study was using 24 mice with 4 treatment groups. Mice were given aspartame during surgical treatment, mice were made to perform measurement of Hb levels, glucose levels and cholesterol levels of neonatal mice. Data analysis using the Kruskal Wallis because Gaussian data but not homogeneous. The results showed an increase in the levels of glucose and cholesterol levels, but statistically there is no difference in glucose levels (p = 0,087), Hb (p = 0,899) and cholesterol (p = 0,168) in mice (Mus musculus) who were given variations of the dose of aspartame.

Item Type: Article
Additional Information: http://jurnalsaintek.uinsby.ac.id/index.php/biotropic/article/view/301
Creators:
Creators
Email
NIDN
Tyastirin, Esti
esty50@gmail.com
UNSPECIFIED
Purnamasari, Risa
risap1989@gmail.com
UNSPECIFIED
Hidayati, Irul
irulhidayati.alfatawi@gmail.com
UNSPECIFIED
Agustina, Eva
eva_agustina@uinsby.ac.id
UNSPECIFIED
Hadi, Moch. Irfan
m_i_h@uinsby.ac.id
UNSPECIFIED
Lusiana, Nova
novalusiana@uinsby.ac.id
UNSPECIFIED
Kumalasari, Mei Lina Fitri
meilina_fitri@uinsby.ac.id
UNSPECIFIED
Uncontrolled Keywords: glucose; cholestero; haemoglobin; aspartame
Subjects: 06 BIOLOGICAL SCIENCES > 0608 Zoology > 060804 Animal Immunology
11 MEDICAL AND HEALTH SCIENCES > 1101 Medical Biochemistry and Metabolomics > 110102 Medical Biochemistry - Carbohydrates
11 MEDICAL AND HEALTH SCIENCES > 1101 Medical Biochemistry and Metabolomics > 110104 Medical Biochemistry - Lipids
11 MEDICAL AND HEALTH SCIENCES > 1101 Medical Biochemistry and Metabolomics > 110106 Medical Biochemistry - Proteins and Peptides (incl. Medical Proteomics)
Divisions: Fakultas Psikologi dan Kesehatan
Depositing User: S.Pd.I Abdun Nashir
Date Deposited: 18 Feb 2022 10:06
Last Modified: 18 Feb 2022 10:06
URI: http://repository.uinsby.ac.id/id/eprint/2166

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